Published evidence

Evidence, not hype.

Transcranial focused ultrasound is an emerging tool for targeted, non-invasive neuromodulation. Human research is growing, while therapeutic applications remain under active investigation.

Scientific Reports · 2018

Legon et al. — Transcranial focused ultrasound neuromodulation of the human primary motor cortex

Human research demonstrating targeted modulation of activity in primary motor cortex.

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Frontiers in Human Neuroscience · 2020

Sanguinetti et al. — Right prefrontal tFUS, mood, and functional connectivity

A randomized placebo-controlled human study reporting changes in self-reported mood and functional connectivity after right prefrontal tFUS.

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Brain Stimulation · 2022

Sarica et al. — Human Studies of Transcranial Ultrasound Neuromodulation

A systematic review of 35 human studies and 677 participants, summarizing effectiveness, safety, and remaining research questions.

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Research cited here does not establish an FDA-approved treatment for depression, PTSD, Alzheimer’s disease, pain, or other conditions. Alamo NeuroVentures presents the evidence to support responsible research and development—not treatment claims.

Research posture

Questions are an asset.

A credible neurotechnology venture should show what has been demonstrated, what remains uncertain, and what must be validated next.

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